Using Pathway Analysis to Understand Biological Phenomena What is a “good” number of DE genes to use in order to try to understand the underlying biological phenomena using a pathway analysis? It is clear [...]
Choosing Differentially Expressed (DE) Genes for the Best Results from Pathway Analysis Pathway Analysis Best Practices This article will answer three key questions Investigators face when doing pathway analysis. What is the best way to choose [...]
Methylprednisolone effective in treating critically ill patients Almost exactly one year ago, the US was experiencing the first wave of COVID-19. In March 2020, SARS-CoV2 is defying all modern medical knowledge and technology killing people at a rate of 1,500 [...]
In a previous post, I wrote about the importance of storytelling in science. This is the other side of the story, the darker side of storytelling, where you decide the story in advance rather than letting your data guide it. [...]
Whether we like it or not, we, as scientists, are judged based on our communication skills. Tenure committees, academic hiring teams, award panels: they all pour over our papers, scoring us on both the number of papers and [...]
AdvaitaBio, a leading provider of bioinformatics to core facilities, researchers and pharmaceutical companies, recently conducted a global poll of bioinformatics service providers in order to determine what factors improve the overall quality, productivity and customer satisfaction.Bioinformatics core facilities and service [...]
You may be interested this recent story in GenomeWeb about how Advaita is taking the lead in the pathway analysis of RNASeq and proteomics data. We are excited that more and more people are gaining access to iPathwayGuide™ and [...]
A while ago, I was doing the pathway analysis of a data set coming from a fat remodeling experiment in mice. This experiment involved a drug candidate known to transform the "regular fat" or white adipose tissue into "brown fat" [...]
Several of our customers have asked us this question: "I am not a core facility, nor do I have a huge lab and therefore I do not have a lot of RNA-Seq data. Should I buy a subscription to [...]
In the world of bioinformatics, we all need to be careful when analyzing our data. I receive countless questions about what background should be used when analyzing gene expression or protein expression data. In this blog post I will [...]
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