About Advaita – Tools for Pathways, miRNAs and Gene Ontology2020-09-08T14:32:12-04:00

Advaita Bioinformatics

We are a leader in the interpretation of high-throughput biomedical data including variant interpretation, pathway analysis, disease subtype discovery and integration of multiple data types. Currently, 9 of the top 10 pharma companies rely on Advaita’s state-of-the-art algorithms to solve complex problems. Advaita provides a suite of advanced analysis software to more that 13,000 registered users worldwide: iPathwayGuide, for functional interpretation of genes and proteins; iVariantGuide, for genetic variant analysis; and iBioGuide, a search engine revealing connections between genes, pathways, SNPs, drugs, and more.

Our Mission

Our mission is to bridge the gap between the ability to collect and interpret biological data.

Advaita Bioinformatics develops bioinformatics data analysis tools with capabilities to integrate multi-‘omic’ data from a systems biology perspective. Our proprietary computational method, Impact Analysis, considers the type, function, position and interaction between genes in a pathway as opposed to other approaches that consider genes to be independent.

Through our $2.2 million NIH STTR Phase II award, we have developed a software platform called Pathway-Guide for the analysis of data from high-throughput microarray and next-generation sequencing experiments. Our next generation product, iPathwayGuide, is a web-based pathway analysis application based on our Impact Analysis method. We are the only company in the industry that includes other crucial factors about the genes in addition to classical statistics. iPathwayGuide includes unique capabilities such modeling SNPs, miRNAs and drugs directly on the pathways and predicting miRNA potentially regulating gene expression in your samples based only on mRNA data. Our vision is to create a platform for multi-omic integration and analysis from a systems biology level.

Advaita Bioinformatics is also working on developing innovative tools for subtyping of diseases and patients. These tools address the classic “responder” vs. “non-responder” problem facing 50% of drugs that reach Phase 3 clinical trials. With our technology, we can identify truly homogeneous populations and the mechanisms that distinguish them from other populations.

Our vision is to:

  • reduce healthcare costs by facilitating efficient decision making for drug development

  • advance personalized medicine by identifying patients with similar underlying disease mechanisms

  • empower researchers to make breakthrough discoveries by analyzing multi-omic data from a systems biology perspective

Our Extraordinary Promise

Our Team Leaders

The Advaita Bioinformatics team is built from a broad range of expertise and backgrounds. We pride ourselves in having the most capable team to deliver the best tools and knowledge for our customers.

Sorin Draghici, Ph.D. – President and CEO2019-11-07T11:12:09-05:00

Advaita BioinformaticsDr. Draghici is a Professor in the Department of Computer Science, and the head of the Intelligent Systems and Bioinformatics Laboratory at Wayne State University. He also holds a joint appointment in the Department Obstetrics and Gynecology and is an Associate Dean in Wayne State University’s College of Engineering. Dr. Draghici is a senior member of IEEE, and an editor of IEEE/ACM Transactions on Computational Biology and Bioinformatics, Protocols in Bioinformatics, Discoveries Journals, Journal of Biomedicine and Biotechnology, and International Journal of Functional Informatics and Personalized Medicine. His publications include two books (”Data Analysis Tools for DNA Microarrays and Statistics” and ”Data Analysis for Microarrays using R”), 8 book chapters, and over 150 peer-reviewed journal and conference publications which gathered over 12,000 citations to date.

Cordelia Ziraldo, Ph.D. – Chief Science Officer and Head of Client Success2019-10-10T17:44:24-04:00

Advaita BioinformaticsAs Chief Science Officer, Dr. Ziraldo leads product development and technical support for Advaita’s state-of-the-art bioinformatics platform. She is passionate about producing software that puts life scientists in the driver’s seat of their data analysis, enabling them to leverage the domain expertise that they uniquely possess instead of relying solely on bioinformaticians. Before joining Advaita, Dr. Ziraldo completed a postdoctoral fellowship at the University of Michigan, working collaboratively between the departments of Chemical Engineering and Microbiology & Immunology. She received her PhD in Computational Biology in 2013 from a joint program between Carnegie Mellon and the University of Pittsburgh.

Anukiran Solur, M.Sc. – Data Visualizations2019-10-10T17:37:00-04:00

Advaita BioinformaticsMs. Anukiran Solur received her MSc in Information and Communication Engineering from the Technical University of Darmstadt in Darmstadt, Germany. Ms. Solur’s expertise is in data visualization using d3.js and other javascript tools.

Careers

Postdoctoral Researcher

AdvaitaBio is searching for an individual with experience and/or interest in the development of bioinformatics and computational biology methods and software. The successful candidate will join a growing team of scientists and developers with a vision for developing an intuitive, easy-to-use SaaS platform for biomedical researchers.

Advaita is a small but fast-growing company that uses artificial intelligence and data science approaches to enable breakthrough discoveries in biomedical research, medicine and drug development. Our scientists are proven mentors and researchers with over 150 publications, over 12,000 citations to their work, over $8 millions in funded grants, and 6 patents issued. Our technology is changing the way research in medicine and drug development is done. Our customers are world-renowned scientists working on game-changing problems in life sciences. Our products help them understand diseases, improve patient outcomes and develop new treatments.

Responsibilities include designing, developing and using advanced, user-friendly bioinformatics tools for the analysis and visualization of biomedical data. The successful candidate will have a PhD in bioinformatics, computational biology, computer science ore related areas. (S)he will have the opportunity to learn and use a modern technology stack including AWS, Docker, Postgres, Javascript, Spring, Angular, etc. They will also have the opportunity to learn grant writing skills, grant management, be involved in successful research and publication activities, etc.

Required skills and experience include:

  • a PhD in bioinformatics, computational biology or related fields
  • experience designing, implementing and using bioinformatics and computational algorithms and methods
  • proficiency in R

Preferred but not required skills include:

  • software development experience
  • Bioconductor
  • Java, Javascript, Python, Angular, AWS, Docker
  • grant writing experience

Advaita offers benefits including health, vision, and dental insurance, a retirement plan, and can also sponsor work visa and green card applicants. Stock options in an extremely promising company are an important component of the compensation package.  Come and have a rewarding software development career while helping to make the world a better place!

Contact us at info@advaitabio.com

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