AdvaitaBio Bioinformatics Logo: Bioinformatics for the Extraordinary
Cores and CROs2021-11-10T21:40:24-05:00

Powering Extraordinary Bioinformatics Core Facilities and Service Providers

Let’s Be Extraordinary Together

Core Facilities support research initiatives across universities. You must balance analysis with tool creation, tool support, training, and administrative duties.

If your customer researchers are intimidated by bioinformatics tools, that forces your Core team to spend time on rework and education, which slows turnaround for new requests.

Get more from your ‘omics data and empower your researcher team to collaborate with the right tools.

pathway analysis software for RNASeq analysis Advaitabio

Multi-Omics Pathway Analysis

From bulk RNA-seq to single cell, from proteomics to epigenetics, our platform delivers powerful insights. Biologists depend on our state-of-the art pathway analysis, gene ontology analysis, upstream regulator predictions, and meta-analysis.

Learn more about iPathwayGuide
variant analysis software AdvaitaBio

Identify & Prioritize Causal Mutations

Annotate and filter VCFs to identify rare, causal, clinically significant variants. Predict effects, impacted pathways and gene ontology terms. Allow customers to explore by sharing the browsable analysis.

Learn more about iVariantGuide
biological analysis software AdvaitaBio

Search Several Databases, All At Once

Find related genes, microRNAs, pathways, biological processes, drugs, diseases, and references. We’ve created google for scientists bringing >108 biological relationships to your fingertips for free.

Learn more about iBioGuide

Extraordinary Customer Experiences

We have earned the trust of bioinformatics core staff and individual researchers. Let them tell you why they use the Advaita Bioinformatics Software Suite.

2021-07-21T10:52:37-04:00

Learn from The Barbara Ann Karmanos Cancer Center

Wei Chen works in the Biostatistics and Bioinformatics Core of the Karmanos Cancer Institute, which is also affiliated with Wayne State University. Located in midtown Detroit, it is the only National Cancer Institute (NCI)-designated comprehensive cancer center in metro Detroit and one of just 51 centers of its kind in the United States...

2021-07-21T10:53:01-04:00

Learn from NIH – Perinatology Research Branch

The Perinatology Research Branch is the only Clinical Branch in the Division of Intramural Research of the National Institutes of Health to focus its research on human pregnancy and unborn children. Using a multidisciplinary approach to study pregnancy complications, the Branch is publishing an average of over 100 peer-reviewed papers per year...

2021-07-21T10:53:29-04:00

Learn from Columbia University

Richard Friedman is an associate research scientist at the Herbert Irving Comprehensive Cancer Center at Columbia University. His bioinformatics analysis activities support about 25 principal investigators (PIs) in any one year. He has been using Advaita’s iPathwayGuide and its predecessor tools for over 15 years...

2021-07-21T10:53:53-04:00

Learn from University of Delaware

Dr. Melinda Duncan is a tenured full professor in the University of Delaware Biological Sciences Department. She performs research in the areas of lens and eye development, cataract surgery and wound healing, and innate immunity. Her research group includes 12 people and uses Advaita software platform to understand and interpret their experimental data...

2021-07-21T10:54:14-04:00

Learn from Morgan State University

Douglas Dluzen, Ph.D., is an Assistant Professor at Morgan State University, a historically black university in downtown Baltimore, Maryland. This public university has added a strong research focus to its long history of educating local and international students. Morgan State is an R2 research university and the premiere public urban research institute in Maryland...

2021-07-21T10:54:48-04:00

Learn from Queen’s University, Belfast

Gary Hardiman is a Professor, School of Biological Science at Queen's University Belfast. Gary began using Advaita’s iPathwayGuide at the Medical University of South Carolina (MUSC). He knew of Advaita from array work that was done a while back and was impressed with the founder and the company. When he moved back to Ireland, he decided to bring iPathwayGuide with him...

2021-07-21T10:55:31-04:00

Learn from SkinAxis

SkinAxis is a biotech company that provides advanced testing technology for skin research. The company focuses on testing, measuring, and monitoring active ingredients for, among other things, antiaging, spot removal and hydration. Pathway analysis is essential to the services it provides to its customers in the cosmetics, biotech, pharmaceutical, chemical, and diagnostics industries...

Analyze Now

  1. Register to explore demo data
  2. Subscribe to analyze your ‘omics data
  3. Review and interact with pathways impacted in your experiment
  4. Share your results with collaborators for interpretation and analysis iteration
  5. Create publication-ready figures simply and easily

What You Can Expect

  • Better Insights
  • Higher Quality
  • Superior Convenience
  • Unmatched Usability
  • Unparalleled Reproducibility
Register to Explore Advaita’s Platform with Demo Data

Get Started!

Get in touch with Advaita to learn how our software will improve quality and efficiency for your Core Facility, Enterprise Bioinformatics team, or Research Lab.

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iPathwayGuide gives a lot of information on different pathways and how they cross react with each other. For example, if you are neuroscientist or immunologist or something else, you may not pay attention to other pathways that could be involved in some other areas. But you do with this iPathwayGuide.

They put all these pathways together. It can actually trigger your thinking in different directions that you never thought about it before. When you look at cross connection of different pathways, it could make new opportunities for your drug discovery. I think it is essential to have this, yes.

Arevik Mosoian, Ph.D., Chief Scientific Officer, SkinAxis

iPathwayGuide is so usable that researchers can actually interact with the data directly. They don’t have to go through a bioinformatic analyst….

If we’ve got a tool that helps those researchers do the research with more independence, that’s the tool that we want everybody to be using.

Bioinformatics Core Director, R1 Research University

I really like the visuals. I interact with and collaborate with a lot of people that aren’t bio-statisticians by background. And the way the data is presented to non-specialists is something that allows them to see what’s going on in a very intuitive way.  iPathwayGuide tells them a story.  It is a wonderful story-telling bioinformatics product.

Gary Hardiman, Professor, Biological Science, Queen's University, Belfast
We tend to use open source tools where we can use them. But the open source tools are not evenly supported, their feature set is sometimes unevenly implemented. And, the licensing model of iPathwayGuide works so much better for the way we work with researchers than any of the commercial competitors in this space. So, it beats both freewar and other commercial products.
Bioinformatics Core Director, R1 Research University

About Advaita Bioinformatics

Our software tools help principal investigators, core facilities, and enterprise bioinformatics teams analyze gene expression data (e.g. RNA-Seq or microarray) and variant data (e.g. DNA-Seq) to find biomarkers, identify impacted pathways, and pinpoint putative mechanisms. Currently, this frustrating process is slow, unreliable, expensive, and often requires multiple disjointed tools, which then provide irrelevant or incorrect results. While other solutions drop a haystack of results on you, we lead you straight to the needle.

Select Publications Citing iPathwayGuide2021-07-22T16:15:51-04:00

Comba, A., Motsch, S., Dunn, P.J., Hollon, T.C., Argento, A.E, Zamler, D.B., Kish, P.E., Kahana, A., Kleer, C.G., Castro, M.G., & Lowenstein, P.R. (2021). Spatiotemporal analysis of glioma heterogeneity reveals Col1A1 as an actionable 1 target to disrupt tumor mesenchymal differentiation, invasion and malignancy. bioRxiv

Duan, S., Nordmeier, S., Byrnes, A.E., & Buxton, I.L.O. (2021). Extracellular vesicle-mediated purinergic signaling contributes to host microenvironment plasticity and metastasis in triple negative breast cancer. International Journal of Molecular Sciences, 22(2), 597.

Helmer, R.A., Martinez-Zaguilan, R., Kaur, G., Smith, L.A., Dufour, J.M., & Chilton, B.S. (2021). Helicase-like transcription factor-deletion from the tumor microenvironment in a cell line-derived xenograft model of colorectal cancer reprogrammed the the human transcriptome-S-nitroso-proteome to promote inflammation and redirect metastasis. PLOS ONE 16(5): e0251132.

Jiagge, E.M., Ulintz, P.J., Wong, S., McDermott, S.P., Fossi, S.I., Suhan, T.K., Hoenerhoff, M.J., Bensenhaver, B.M., Salem, B., Dziubinski, M., Oppong, J.K., Aitpillah, F., Ishmael, K., Osei-Bonsu, E., Adjei, E., Baffour, A., Aldrich, J., Kurdoglu, A., Fernando, K., Draig, D.W., Trent, J.M., Li, J., Chitale, D., Newman, L.A., Carpten, J.D., Wicha, M.S., & Merajver, S.D. (2021). Multiethnic PDX models predict a possible immune signature associated with TNBC of African ancestry. Breast Cancer Research and Treatment, 186, 391-401.

Kishimoto, K., Kanazawa., K, Nomura, M., Tanaka, T., Shigemoto-Kuroda, T., Fukui, K., Kurosawa, K., Kawai, M., Kato, H., Terasaki, K., Sakamoto, Y., Yamashita, Y., Sato, I., Tanuma, N., Tamai, K., Kitabayashi, I., Matsuura, K., Watanabe, T., Yasuda, J., Tsuji, H., & Shima, H. (2021). Ppp6c deficiency accelerates K‐rasG12D‐induced tongue carcinogenesis. Cancer Medicine, 10(13), 4451-4464.

Krieg, C., Carloni, S., Weber, L.M., Fosso, B., Hardiman, G., Mileti, E., El Aidy, S., Marzano, M., Pesole, G., Asnicar, F., Segata, N., Robinson, M.D., & Guglietta, S. (2021). Loss of C3aR induces immune infiltration and inflammatory microbiota in a novel spontaneous model of colon cancer. bioRxiv.

Lidberg, K.A., Muthusamy, S., Adil, M., Patel, R.S., Wang, L., Bammler, T.K., Reichel, J., Yeung, C.K., Himmelfarb, J., Kelly, E.J., & Shreeram, A., (2021). Multi-omic Characterization of Human Tubular Epithelial Cell Response to Serum. bioRxiv.

Liu, J., Qiu, J., Zhang, Z., Zhou, L., Li, Y., Ding, D., Zhang, Y., Zou, D., Wang, D., Zhou, Q., & Lang, T. (2021). SOX4 maintains the stemness of cancer cells via transcriptionally enhancing HDAC1 revealed by comparative proteomics study. Cell Biosci, 11, 23.

Merritt, N., Garcia, K,. Rajendran, D., Lin, Z.Y., Zhang, X., Mitchell, K.A., Borcherding, N., Fullenkamp, C., & Chimenti, M.S. (2021). TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. eLife, 10:e62857.

Tsuji, Y., Nonoguchi, N., Okuzaki, D., Wada, Y., Motooka, D., Hirota, Y., Toho, T., Yoshikawa, N., Furuse, M., Kawabata, S., Miyatai, S.I., Nakamura, H., Yamamoto, R., Nakamura, S., Kuroiwa, T., & Wanibuchi, M. (2021). The Up-Regulation of CXCL12-CXCR4 Axis By Radiotherapy Could Accelerate Glioma Progression., Research Square.

Weber, H., Ruoff, R., & Garabedian, M.J. (2021). MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen. PLOS Genetics, 17(1): e1008540.

Wesley, Y.Y., Hill, S.T., Chan, E.R., Pink, J.J., Cooper, K., Leachman, S., Lund, A.W., Kulkarni, R., & Bordeaux, J.S. (2021). Computational Drug Repositioning Identifies Statins as Modifiers of Prognostic Genetic Expression Signatures and Metastatic Behavior in Melanoma. Journal of Investigative Dermatology, 141(7), 1802-1809.

Wills, C.A., Liu, X., Chen, L., Zhao, Y., Dower, C.M., Sundstrom, J., & Wong, H.G. (2021). Chemotherapy-induced upregulation of small extracellular vesicle-associated PTX3 accelerates breast cancer metastasis. Cancer Research, 81(2), 452-463.

Argento, A.E., Kadiyala, P., Ventosa, M., Patel, P., Zamler, D.B., Nunez, F.J., Zhao, L., Castro, M.G., & Lowenstein, P.R. (2020). Fyn tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates antiglioma immune responses. Neuro-Oncology, 22(6), 806-818.

Balogh, A., Reiniger, L., Hetey, S., Kiraly, P., Toth, E., Karaszi, K., Juhasz, K., Gelencser, Z., Zvara, A., Szilagyi, A., Puskas, L.G., Matko, J., Papp, Z., Kovalszky, I., Juhasz, C., & Than, N.G. (2020). Decreased Expression of ZNF554 in Gliomas is Associated with the Activation of Tumor Pathways and Shorter Patient Survival. International Journal of Molecular Sciences, 21(16):5762.

Caro, D., Rivera, D., Ocampo, Y., Müller, K., & Franco, L.A., (2020). A promising naphthoquinone [8-hydroxy-2-(2-thienylcarbonyl) naphtho [2, 3-b] thiophene-4, 9-dione] exerts anti-colorectal cancer activity through ferroptosis and inhibition of MAPK signaling pathway based on RNA sequencing. Open Chemistry, 18(1):1242-1255.

Fernández, G., Jose, M. (2020). In vitro antitumor activity of arachidonic and docosahexaenoic acids as both monoacylglycerols and free fatty acids on colorectal cancer cells., Tesis Universidad de Almeria [90].

Herkenne, S., Ek, O., Zamberlan, M., Pellattiero, A., Chergova, M., Chivite, I., Novotna, E., Rigoni, G., Fonseca, T.B., Samardzic, D., Agnellini, A., Bean, C., Beneditti, G.D., Tiso, N., Argenton, F., Viola, A., Soriano, M.E., Giacomello, M., Ziviani, E., Sales, G., Claret, M., Graupera, M., & Scorrano, L. (2020). Developmental and tumor angiogenesis requires the mitochondria-shaping protein Opa1. Cell Metabolism, 31(5), 987-1003.e8.

Mendez, F., Kadiyala, P., Nunez, F.J., Carney, S., Nunez, F.M., Gauss, J.C., Ravindran, R., Pawar, S., Edwards, M, Garcia-Fabiani, M.B., Haase, S., Lowenstein, P.R., & Castro, M.G. (2020). Therapeutic efficacy of immune stimulatory thymidine kinase and fms-like tyrosine kinase 3 ligand (TK/Flt3L) gene therapy in a mouse model of high-grade brainstem glioma. Clinical Cancer Research, 26(15), 4080-4092.

Nagesh, P.K.B., Chowdhury, P., Hatami, E., Jain, S., Dan, N., Kashyap, V.K., Chauhan, S.C., Jaggi, M., & Yallapu, M.M. (2020). Tannic acid inhibits lipid metabolism and induce ROS in prostate cancer cells. Sci Rep, 10, 980.

Ocampo, Y., Caro, D., Rivera, D., Piermattey, J., Gaitan., R., & Franco, L.A. (2020). Transcriptome Changes in Colorectal Cancer Cells upon Treatment with Avicequinone B, Advanced Pharmaceutical Bulletin, 10(4), 638–647.

Sarmiento-Castro, A., Caamaño-Gutiérrez, E., Sims, A.H., Hull, N.J., James, M.I., Santiago-Gomez, A., Eyre, R., Clark, C., Brown, M.E., Brooks, M.D., Wicha, M.S., Howell, S.J., Clarke, R.B., Simoes, B.M. (2020). Increased expression of interleukin-1 receptor characterizes anti-estrogen-resistant ALDH+ breast cancer stem cells. Stem Cell Reports, 15(2), 307-316.

Ulm, M.A., Redfern, T.M., Wilson, B.R., Ponnusamy, S., Asemota, S., Blackburn, P.W., Wang, Y., ElNaggar, A.C., & Nararyanan, R. (2020). Integrin-Linked Kinase Is a Novel Therapeutic Target in Ovarian Cancer. Journal of Personalized Medicine, 10(4), 246.

Verma, S., Shankar, E., Chan, E.R., & Gupta, S. (2020). Metabolic Reprogramming and Predominance of Solute Carrier Genes during Acquired Enzalutamide Resistance in Prostate Cancer. Cells, 9(12), 2535.

Yong, K.M.A., Ulintz, P.J., Caceres, S., Cheng, X., Bao, L., Wu, Z., Jiagge, E.M., & Merajver, S.D., (2020). Heterogeneity at the invasion front of triple negative breast cancer cells. Sci Rep, 10, 5781.

Liu, Y., Lang, T., Jin, B., Chen, F., Zhang, Y., Beuerman, R.W., Zhou, L. and Zhang, Z., 2017. Luteolin inhibits colorectal cancer cell epithelial-to-mesenchymal transition by suppressing CREB1 expression revealed by comparative proteomics study. Journal of proteomics 161, pp.1-10.

Han, K., Lang, T., Zhang, Z., Zhang, Y., Sun, Y., Shen, Z., Beuerman, R.W., Zhou, L. and Min, D., 2018. Luteolin attenuates Wnt signaling via upregulation of FZD6 to suppress prostate cancer stemness revealed by comparative proteomics. Scientific reports, 8(1), p.8537.

Ortea, I., González-Fernández, M. J., Ramos-Bueno, R. P., & Guil-Guerrero, J. L. (2018). Proteomics study reveals that docosahexaenoic and arachidonic acids exert different in vitro anticancer activities in colorectal cancer cells. Journal of agricultural and food chemistry, 66(24), 6003-6012.

Wagner, S., Ball, G. R., Pockley, A. G., & Miles, A. K. (2018). Application of omic technologies in cancer research. Translational Medicine Reports, 2(1).

Mrowczynski, O.D., Madhankumar, A.B., Sundstrom, J.M., Zhao, Y., Kawasawa, Y.I., Slagle-Webb, B., Mau, C., Payne, R.A., Rizk, E.B., Zacharia, B.E. and Connor, J.R., 2018. Exosomes impact survival to radiation exposure in cell line models of nervous system cancer. Oncotarget, 9(90), p.36083.

Zeinali, M., Murlidhar, V., Fouladdel, S., Shao, S., Zhao, L., Cameron, H., Bankhead III, A., Shi, J., Cuneo, K.C., Sahai, V. and Azizi, E., 2018. Profiling Heterogeneous Circulating Tumor Cells (CTC) Populations in Pancreatic Cancer Using a Serial Microfluidic CTC Carpet Chip. Advanced Biosystems, 2(12), p.1800228.

Rücker, F. G., Dolnik, A., Blätte, T. J., Teleanu, V., Ernst, A., Thol, F., … & Bullinger, L. (2018). Chromothripsis is linked to TP53 alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype. haematologica, 103(1), e17-e20.

Araújo, T., Khayat, A., Quintana, L., Calcagno, D., Mourão, R., Modesto, A., Paiva, J., Lima, A., Moreira, F., Oliveira, E. and Souza, M., 2018. Piwi like RNA-mediated gene silencing 1 gene as a possible major player in gastric cancer. World journal of gastroenterology, 24(47), 5338.

Ock, S., Ahn, J., Lee, S.H., Kim, H.M., Kang, H., Kim, Y.K., Kook, H., Park, W.J., Kim, S., Kimura, S. and Jung, C.K., 2018. Thyrocyte‐specific deletion of insulin and IGF‐1 receptors induces papillary thyroid carcinoma‐like lesions through EGFR pathway activation. International Journal of Cancer, 143(10), pp.2458-2469.

Renz, B.W., Tanaka, T., Sunagawa, M., Takahashi, R., Jiang, Z., Macchini, M., Dantes, Z., Valenti, G., White, R.A., Middelhoff, M.A. and Ilmer, M., 2018. Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness. Cancer discovery, 8(11), pp.1458-1473.

Luo, M., Shang, L., Brooks, M.D., Jiagge, E., Zhu, Y., Buschhaus, J.M., Conley, S., Fath, M.A., Davis, A., Gheordunescu, E. and Wang, Y., 2018. Targeting breast cancer stem cell state equilibrium through modulation of redox signaling. Cell metabolism, 28(1), pp.69-86.

Todorova, K., Metodiev, M.V., Metodieva, G., Mincheff, M., Fernández, N. and Hayrabedyan, S., 2016. Micro-RNA-204 Participates in TMPRSS2/ERG Regulation and Androgen Receptor Reprogramming in Prostate Cancer. Hormones and Cancer, pp.1-21.

Simonik, E.A., Cai, Y., Kimmelshue, K.N., Brantley-Sieders, D.M., Loomans, H.A., Andl, C.D., Westlake, G.M., Youngblood, V.M., Chen, J., Yarbrough, W.G. and Brown, B.T., 2016. LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer). PloS one, 11(10), p.e0164804.

Klener, P., Fronkova, E., Berkova, A., Jaksa, R., Lhotska, H., Forsterova, K., Soukup, J., Kulvait, V., Vargova, J., Fiser, K. and Prukova, D., 2016. Mantle cell lymphoma‐variant Richter syndrome: Detailed molecular‐cytogenetic and backtracking analysis reveals slow evolution of a pre‐MCL clone in parallel with CLL over several years. International Journal of Cancer.

Colacino, J.A., McDermott, S.P., Sartor, M.A., Wicha, M.S. and Rozek, L.S., 2016. Transcriptomic profiling of curcumin-treated human breast stem cells identifies a role for stearoyl-coa desaturase in breast cancer prevention.Breast Cancer Research and Treatment, pp.1-13.

Kravchenko, D.S., Lezhnin, Y.N., Kravchenko, J.E., Chumakov, S.P. and Frolova, E.I., 2016. Study of Molecular Mechanisms of PDLIM4/RIL in Promotion of the Development of Breast Cancer. Biol Med (Aligarh), 8(2), p.2.

Na, Y., Kaul, S.C., Ryu, J., Lee, J.S., Ahn, H.M., Kaul, Z., Kalra, R.S., Li, L., Widodo, N., Yun, C.O. and Wadhwa, R., 2016. Stress chaperone mortalin contributes to epithelial-mesenchymal transition and cancer metastasis.Cancer research, pp.canres-2704.

Sanford, T., Welty, C., Meng, M. and Porten, S., 2015. MP68-18 MOLECULAR ANALYSIS OF UROTHELIAL TUMORS IN PATIENTS WITH AND WITHOUT METASTASIS STRATIFIED BY T STAGE. The Journal of Urology, 193(4), p.e865.

Hernandez, C., Huebener, P., Pradere, J. P., Antoine, D. J., Friedman, R. A., & Schwabe, R. F. (2018). HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis. The Journal of clinical investigation, 128(6).

Bacich, Dean, Wasim H. Chowdhury, Ronald Rodriguez, and Zhiping Wang. “Increased expression of TRIP13 drives the tumorigenesis of bladder cancer in association with the EGFR signaling pathway.”

Racioppi, L., Nelson, E.R., Huang, W., Mukherjee, D., Lawrence, S.A., Lento, W., Masci, A.M., Jiao, Y., Park, S., York, B. and Liu, Y., 2019. CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer. Nature communications, 10(1), p.2450.

Cartwright, R., Franklin, L., Tikkinen, K.A.O., Kalliala, I., Miotla, P., Rechberger, T., Offiah, I., McMahon, S., O’Reilly, B., Lince, S., Kluivers, K., Post, W., Poelmans, G., Palmer, M.R., Wessels, H., Wong, A., Kuh, D., Kivimaki, M., Kumari, M., Mangino, M., Spector, T., Guggenheim, J.A., Lehne, B., De Silva, N.M.G., Evans, D.M., Lawlor, D., Karhunen, V., Mannikko, M., Marczak, M., Bennett, P.R., Khullar, V., Järvelin, M.R., &Walley, A. (2021). Genome wide association study identifies two novel loci associated with female stress and urgency urinary incontinence. Journal of Urology.

Cortes-Selva, D., Gibbs, L., Maschek, J.A., Nascimento, M., Van Ry, T., Cox, J.E., Amiel, E., & Fairfax, K.C. (2021). Metabolic reprogramming of the myeloid lineage by Schistosoma mansoni infection persists independently of antigen exposure. PLOS Pathogens, 17(1): e1009198.

Gomez-Lopez, N., Romero, R., Varrey, A., Leng, Y., Miller, D., Done, B., Xu. Y., Bhatti, G., Motomura, K., Gershater, M., Pique-Regi, R., & Tarca, A.L. (2021). RNA sequencing reveals diverse functions of amniotic fluid neutrophils and monocytes/macrophages in intra-amniotic infection. Journal of Innate Immunity, 13, 63-82.

Motomura, K., Romero, R., Galaz, J., Tarca, A.L., Done, B., Xu, Y., Leng, Y., Garcia-Flores, V., Arenas-Hernandez, M., Theis, K.R., Gershater, M., Jung, E., Hsu, C.D., & Gomez-Lopez, N. (2021). RNA sequencing reveals distinct immune responses in the chorioamniotic membranes of women with preterm labor and microbial or sterile intra-amniotic inflammation. Infection and Immunity, 89(5): e00819-20.

Stein, M.M., Conery, M., Magnaye, K.M., Clay, S.M., Billstrand, C., Nicolae, R., Naughton, K., Ober, C., & Thompson, E.E. (2021). Sex-specific differences in peripheral blood leukocyte transcriptional response to LPS are enriched for HLA region and X chromosome genes. Scientific Reports, 11, 1107.

Wang, Z., Chimenti, M.S., Strouse, C., & Weiner, G.J. (2021). T cells, particularly activated CD4+ cells, maintain anti-CD20-mediated NK cell viability and antibody dependent cellular cytotoxicity. Cancer Immunology, Immunotherapy.

Motomura, K., Romero, R., Tarca, A.L., Galaz, J., Bhatti, G., Done, B., Arenas-Hernandez, M., Chaur, D., & Gomez-Lopez, N. (2020). Pregnancy-specific transcriptional changes upon endotoxin exposure in mice. Journal of Perinatal Medicine, 48(7), 700-722.

Rahman, A.A., Soto-Avellaneda, A., Jin, H.Y., Stojkovska, I., Lai, N.K., Albright, J.E., Webb, A.R., Oe, E., Valarde, J.P., Oxford, A.E., Urquhart, P.E., Wagner, B., Brown, C., Amado, I., Vasquez, P., Lehning, N., Grozdanov, V., Pu, X., Danzer, K.M., & Morrison, B.E. (2020). Enhanced Hyaluronan Signaling and Autophagy Dysfunction by VPS35 D620N. Neuroscience, 441, 33-45.

Schlievert, P.M., Gourronc, F.A., Leung, D.Y.M., & Klingelhutz, A.J. (2020). Human Keratinocyte Response to Superantigens. mSphere, 5(5): e00803-20.

Tchessalova, D., & Tronson, N.C. (2020). Enduring and sex-specific changes in hippocampal gene expression after a subchronic immune challenge. Neuroscience, 428, 76-89.

Van Den Broek, B., Pintelon, I., Hamad, I., Kessels, S., Haidar, M., Hellings, N., Hendriks, J.J.A., Kleinewietfeld, M., Brone, B., Timmerman, V., Timmermans, J.P., Somers, V., Michiels, L., & Irobi, J. (2020). Microglial derived extracellular vesicles activate autophagy and mediate multi‐target signaling to maintain cellular homeostasis. Journal of Extracellular Vesicles, 10(1).

Wu, Q., Mills, E.A., Wang, Q., Dowling, C.A., Fisher, C.,  Kirch, B., Lundy, S.K., Fox, D.A., & Mao-Draayer, Y. (2020). Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis. JCI Insight, 5(3): e134251.

Fuentes-González, A.M., Muñoz-Bello, J.O., Manzo-Merino, J., Contreras-Paredes, A., Pedroza-Torres, A., Fernández-Retana, J., Pérez-Plasencia, C. and Lizano, M., 2019. Intratype variants of the E2 protein from human papillomavirus type 18 induce different gene expression profiles associated with apoptosis and cell proliferation. Archives of virology, pp.1-14.

Chakraborty, P., Kuo, R., Vervelde, L., Dutia, B. M., Kaiser, P., & Smith, J. (2019). Macrophages from Susceptible and Resistant Chicken Lines have Different Transcriptomes following Marek’s Disease Virus Infection. Genes, 10(2), 74.

Cortes-Selva, D., Elvington, A. F., Ready, A., Rajwa, B., Pearce, E. J., Randolph, G. J., & Fairfax, K. C. (2018). Schistosoma mansoni infection-induced transcriptional changes in hepatic macrophage metabolism correlate with an athero-protective phenotype. Frontiers in Immunology, 9.

Tjitro, R., Campbell, L. A., Basova, L., Johnson, J., Najera, J. A., Lindsey, A., & Marcondes, M. C. G. (2018). Modeling the Function of TATA Box Binding Protein in Transcriptional Changes Induced by HIV-1 Tat in Innate Immune Cells and the Effect of Methamphetamine Exposure. Frontiers in immunology, 9.

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