On February 27, 2017, Advaita released a major updates to its platform. These are the release notes.
IMPROVEMENTS TO: iPathwayGuide, iVariantGuide, iBioguide, and the Advaita Knowledge Base
- Changes to AWS services in preparation for HIPAA compliance
- Updated knowledge base to version Advaita KB v1702, which includes the following data sources and versions:
| Database | Version | iPG Annotations | iVG Annotations |
|---|---|---|---|
| KEGG | Release 81.0+/01-20, Jan 17 | Pathways, Diseases, Drugs | Pathways |
| Gene Ontology | 2016-Sep26 | GO Terms | GO Terms |
| Targetscan | Targetscan v7.1 | miRNA Target Genes | miRNA Target Genes |
| MIRBASE | MIRBASE v21,06/14 | miRNA Sequences | |
| dbSNP (incl 1k genomes) | Build 149 | Minor Allele freq. | |
| RefSeq | Release 71 July 2016 | Impacted Transcripts | |
| ClinVar | Dec 1, 2016 | Clinical Significance | |
| SNPEff | v4.1L | Predicted Impact |
IMPROVEMENTS TO iPATHWAYGUIDE
- NEW FEATURE! Onboarding carousel with top user benefits
- NEW FEATURE! API (Premium feature)
- Bug fix: genes selected in Genes Table on Pathways page are now highlighted on pathway map
IMPROVEMENTS TO iVARIANTGUIDE
- Improved error messaging for sample upload & report creation
- NEW FEATURE! Versioning: each report now shows which version of the Advaita Knowledgebase was used to annotate the sample. Outdated reports may be updated when viewing Report Info: either on the Reports page or from within the report itself. As is true for other Advaita applications, only the report owner may update it.
IMPROVEMENTS TO iBIOGUIDE
- Updated to use AKB v1702