iVariantGuide takes your vcf file and will ensure it is annotated with multiple sources and then provides a number of interactive filters for you to see relationships between various biological features and/or effects. With other variant analysis or interpretation applications, you must know exactly the tradeoff you are making when selecting your filters to go from 100,000+ variants to a manageable list of a few, 50, or whatever number of variants fits your criteria. With iVariantGuide, we let you explore these tradeoffs in real-time with intuitive filters that update immediately. This lets you explore relationships like those that may exist between pathogenic variants and chromosomal locations.
VariantGuide gives you simple and easy tools to save sets of filters (presets) and apply them to other samples. You can even share your filter preset and analysis with others simply by entering their email address.