Learning Center – Pathway Analysis
Pathway analysis turns a list of differentially expressed genes into a defensible biological mechanism. This Learning Center track covers pathway analysis workflows, from Impact Analysis versus enrichment approaches to results grounded in peer-reviewed science, using guided methods your team can validate and reproduce. Explore the articles below to see how iPathwayGuide™ takes your gene list from differential expression to mechanistic insight, in minutes, not weeks.
Pathway Analysis Method Review
A comprehensive review and assessment of pathway analysis methods Genome Biology recently published a peer-reviewed paper containing a comprehensive benchmarking and comparison of 13 widely-used pathway analysis methods across more than 1,000 analyses. We highlight the most important [...]
Pathway Analysis vs Gene Set Analysis
Pathway Analysis vs Gene Set Analysis What is the Difference and When Should I Use Each? To some, pathway analysis and gene set analysis are synonyms. However, there are important distinctions between these [...]
Pathway Analysis Method Validation
How do you validate a pathway analysis method? How do you compare such methods? My previous post, Pathway Analysis vs Gene Set Analysis, ended with an interesting question: has anybody really compared side-by-side gene [...]
Enrichment vs Impact Pathway Analysis
Not getting much from your pathway analysis? Use Impact Analysis instead of Enrichment alone. How are you currently analyzing your RNASeq and proteomics data? Are you currently using one of the [...]