Advaita Blog and News
10 Criteria for Extraordinary Bioinformatics
Now more than ever, bioinformatics analysis is crucial for the success of almost any life science research program How do you take the right approach for your question and your data? Do you: Choose the approach or software [...]
Evaluation Criteria for Extraordinary Bioinformatics
We’re conducting a 7-minute survey to better understand how life scientists are approaching their data analysis. To show our appreciation, those who successfully complete it will be entered to win a pair of wireless earbuds (your choice of AirPods or Pixel [...]
Six qualities that your bioinformatics software must have
AdvaitaBio, a leading provider of bioinformatics to core facilities, researchers and pharmaceutical companies, recently conducted a global poll of bioinformatics service providers in order to determine what factors improve the overall quality, productivity and customer satisfaction. Bioinformatics core facilities [...]
iPathwayGuide’s prediction for a COVID-19 drug validated in clinical study
Methylprednisolone effective in treating critically ill patients Recently, we announced that Advaita’s advanced AI platform, iPathwayGuide, was able to predict an existing drug with clinical efficacy against COVID-19. While the manuscript undergoes peer review, a preprint is available from Nature Research. Read [...]
A comprehensive review and assessment of pathway analysis methods
Genome Biology recently published a peer-reviewed paper containing a comprehensive benchmarking and comparison of 13 widely-used pathway analysis methods across more than 1,000 analyses. We highlight the most important findings below. The problem: Many high-throughput experiments compare two phenotypes [...]
Advaita’s iPathwayGuide provides a cost-effective alternative to Ingenuity Pathway Analysis (IPA) on Yet Another Continent
Inqaba Biotechnical Industries partners with Advaita Bioinformatics to provide advanced pathway analysis software in Sub-Saharan Africa ANN ARBOR, MI – October 14, 2019— Advaita Bioinformatics, the leader in the interpretation of high-throughput biomedical data, today announced a new distribution partnership [...]
What’s the difference between iPathwayGuide and Ingenuity Pathway Analysis (IPA)?
You might think that spending thousands of dollars to meet your bioinformatics needs guarantees the most accurate analysis on the market. Well, it’s actually a lot more complicated than that! Expensive pathway analysis tools such as Qiagen’s Ingenuity Pathway Analysis [...]
iPathwayGuide is Perfect for Bioinformatics Cores and Service Providers
Is this you? You provide expert bioinformatics services to your organization You have great analysts in your group, but not enough of them Your organization does extremely important work in biomedical research, but you have to live on a budget [...]
Not getting much from your pathway analysis? Use Impact Analysis instead of Enrichment alone.
How are you currently analyzing your RNASeq and proteomics data? Are you currently using one of the many free tools available for pathway analysis, such as DAVID? Or, are you perhaps using Qiagen's IPA? If yes, you are using an [...]
Advaita is taking the lead…
You may be interested this recent story in GenomeWeb about how Advaita is taking the lead in the pathway analysis of RNASeq and proteomics data. We are excited that more and more people are gaining access to iPathwayGuide and [...]
Advaita Scientists Awarded Another Pathway Analysis Patent
A while ago, I was doing the pathway analysis of a data set coming from a fat remodeling experiment in mice. This experiment involved a drug candidate known to transform the "regular fat" or white adipose tissue into "brown fat" [...]
iPathwayGuide Analysis Finds Both Overlapping and Species-Specific Endocrine Disrupting Chemical Response Signatures in Sardine and Mackerel
Orthologs in Systems Biology A recent paper by Renaud, et al., (Environmental Pollution, Vol 244, January 2019, pp 926-937) points out the significant hazard posed by endocrine disrupting chemical (EDC) exposure for aquatic organisms. Renaud, et al., employed iPathwayGuide as [...]
Advaita Bioinformatics displaces major competitor in Australia and New Zealand
Advaita announces new distribution partnership with Millennium Science. ANN ARBOR, Michigan, April 23, 2019 – Advaita Bioinformatics, provider of the industry-leading gene expression and genomic variation analysis platform, announces a new partnership with Millennium Science for distribution of Advaita’s software [...]
How do you validate a pathway analysis method? How do you compare such methods?
My previous post, Pathway Analysis vs Gene Set Analysis, ended with an interesting question: has anybody really compared side-by-side gene set analysis methods and pathway analysis methods on the same data sets? Well, the answer is: not yet! The [...]
Pathway Analysis vs Gene Set Analysis: What is the Difference and When Should I Use Each?
To some, pathway analysis and gene set analysis are synonyms. However, there are important distinctions between these two groups of methods, and they provide different results. This is part of a series of articles on pathway analysis methods. Pathway analysis [...]