Advaita Blog and News
How do I know if a pathway is “up-regulated” or “down-regulated”?
We often hear the following question: "Is there any way to know if the whole pathway or the whole GO is upregulated or downregulated? The results table shows p-values and DE numbers, but I want to know if that [...]
5 ways to analyze your omics data without paying for software
You are a life scientist undertaking cutting edge research that involves experiments in which you collect omics data: transcriptomics, genomics, proteomics, methylation, RNASeq, ATACSeq, single cell, etc. You are working on an exciting and very important problem. You have great [...]
Make sure the odds are in your favor.
In the world of bioinformatics, we all need to be careful when analyzing our data. I receive countless questions about what reference set should be used when analyzing gene expression or protein expression data. If you are thinking “what’s a [...]
iPathwayGuide’s prediction for a COVID-19 drug validated, peer-reviewed and published!
Methylprednisolone effective in treating critically ill patients Almost exactly one year ago, the US was experiencing the first wave of COVID-19. In March 2020, SARS-CoV2 is defying all modern medical knowledge and technology killing people at a rate of 1,500 [...]
Webinar: How Do You Know If It Is Time To Change Your Bioinformatics Software
Bioinformatics leaders always want to know if they have the right solution for their organization. There are 12 essential factors to evaluate to determine if change is needed. This webinar will explore those 12 factors and provide practical advice [...]
Science Storytelling Done Backwards
In a previous post, I wrote about the importance of storytelling in science. This is the other side of the story, the darker side of storytelling, where you decide the story in advance rather than letting your data guide it. [...]
Extraordinary software saves, not wastes your time
It's such a familiar scenario: you sit with the scientist or a collaborator to understand their research question, perform the analysis, and present your results. Then, a week later, you get an email asking for a whole new analysis of [...]
Storytelling is an essential component of Extraordinary Bioinformatics
Whether we like it or not, we, as scientists, are judged based on our communication skills. Tenure committees, academic hiring teams, award panels: they all pour over our papers, scoring us on both the number of papers and [...]
10 Criteria for Extraordinary Bioinformatics
Now more than ever, bioinformatics analysis is crucial for the success of almost any life science research program How do you take the right approach for your question and your data? Do you: Choose the approach or software [...]
Evaluation Criteria for Extraordinary Bioinformatics
We’re conducting a 7-minute survey to better understand how life scientists are approaching their data analysis. To show our appreciation, those who successfully complete it will be entered to win a pair of wireless earbuds (your choice of AirPods or [...]
Six qualities that your bioinformatics software must have
AdvaitaBio, a leading provider of bioinformatics to core facilities, researchers and pharmaceutical companies, recently conducted a global poll of bioinformatics service providers in order to determine what factors improve the overall quality, productivity and customer satisfaction. Bioinformatics core facilities [...]
A comprehensive review and assessment of pathway analysis methods
Genome Biology recently published a peer-reviewed paper containing a comprehensive benchmarking and comparison of 13 widely-used pathway analysis methods across more than 1,000 analyses. We highlight the most important findings below. The problem: Many high-throughput experiments compare two phenotypes [...]
Advaita’s iPathwayGuide provides a cost-effective alternative to Ingenuity Pathway Analysis (IPA) on Yet Another Continent
Inqaba Biotechnical Industries partners with Advaita Bioinformatics to provide advanced pathway analysis software in Sub-Saharan Africa ANN ARBOR, MI – October 14, 2019— Advaita Bioinformatics, the leader in the interpretation of high-throughput biomedical data, today announced a new distribution partnership [...]
What’s the difference between iPathwayGuide and Ingenuity Pathway Analysis (IPA)?
You might think that spending thousands of dollars to meet your bioinformatics needs guarantees the most accurate analysis on the market. Well, it’s actually a lot more complicated than that! Expensive pathway analysis tools such as Qiagen’s Ingenuity Pathway Analysis [...]
iPathwayGuide is Perfect for Bioinformatics Cores and Service Providers
Is this you? You provide expert bioinformatics services to your organization You have great analysts in your group, but not enough of them Your organization does extremely important work in biomedical research, but you have to live on a budget [...]