Advaita Blog and News
A comprehensive review and assessment of pathway analysis methods
Genome Biology recently published a peer-reviewed paper containing a comprehensive benchmarking and comparison of 13 widely-used pathway analysis methods across more than 1,000 analyses. We highlight the most important findings below. The problem: Many high-throughput experiments compare two phenotypes [...]
Advaita’s iPathwayGuide provides a cost-effective alternative to Ingenuity Pathway Analysis (IPA) on Yet Another Continent
Inqaba Biotechnical Industries partners with Advaita Bioinformatics to provide advanced pathway analysis software in Sub-Saharan Africa ANN ARBOR, MI – October 14, 2019— Advaita Bioinformatics, the leader in the interpretation of high-throughput biomedical data, today announced a new distribution partnership [...]
What’s the difference between iPathwayGuide and Ingenuity Pathway Analysis (IPA)?
You might think that spending thousands of dollars to meet your bioinformatics needs guarantees the most accurate analysis on the market. Well, it’s actually a lot more complicated than that! Expensive pathway analysis tools such as Qiagen’s Ingenuity Pathway Analysis [...]
iPathwayGuide is Perfect for Bioinformatics Cores and Service Providers
Is this you? You provide expert bioinformatics services to your organization You have great analysts in your group, but not enough of them Your organization does extremely important work in biomedical research, but you have to live on a budget [...]
Advaita is taking the lead…
You may be interested this recent story in GenomeWeb about how Advaita is taking the lead in the pathway analysis of RNASeq and proteomics data. We are excited that more and more people are gaining access to iPathwayGuide and [...]
Advaita Scientists Awarded Another Pathway Analysis Patent
A while ago, I was doing the pathway analysis of a data set coming from a fat remodeling experiment in mice. This experiment involved a drug candidate known to transform the "regular fat" or white adipose tissue into "brown fat" [...]
iPathwayGuide Analysis Finds Both Overlapping and Species-Specific Endocrine Disrupting Chemical Response Signatures in Sardine and Mackerel
Orthologs in Systems Biology A recent paper by Renaud, et al., (Environmental Pollution, Vol 244, January 2019, pp 926-937) points out the significant hazard posed by endocrine disrupting chemical (EDC) exposure for aquatic organisms. Renaud, et al., employed iPathwayGuide as [...]
Advaita Bioinformatics displaces major competitor in Australia and New Zealand
Advaita announces new distribution partnership with Millennium Science. ANN ARBOR, Michigan, April 23, 2019 – Advaita Bioinformatics, provider of the industry-leading gene expression and genomic variation analysis platform, announces a new partnership with Millennium Science for distribution of Advaita’s software [...]
How do you validate a pathway analysis method? How do you compare such methods?
My previous post, Pathway Analysis vs Gene Set Analysis, ended with an interesting question: has anybody really compared side-by-side gene set analysis methods and pathway analysis methods on the same data sets? Well, the answer is: not yet! The [...]
Pathway Analysis vs Gene Set Analysis: What is the Difference and When Should I Use Each?
To some, pathway analysis and gene set analysis are synonyms. However, there are important distinctions between these two groups of methods, and they provide different results. This is part of a series of articles on pathway analysis methods. Pathway [...]
Subscription vs. purchasing individual analyses – which one do I want?
Several of our customers have asked us this question: "I am not a core facility, nor do I have a huge lab and therefore I do not have a lot of RNA-Seq data. Should I buy a subscription to iPathwayGuide [...]
AdvaitaBio releases a new version of iPathwayGuide, the world’s most advanced RNA-seq and gene expression analysis software
Advaita Bioinformatics is announcing a new release of iPathwayGuide, the world’s most advanced RNA-seq and gene expression analysis software. This release includes unprecedented gene network analysis and literature mining capabilities. The newly added network analysis capabilities allow the scientists to [...]
When did you do your last background check?
In the world of bioinformatics, we all need to be careful when analyzing our data. I receive countless questions about what background should be used when analyzing gene expression or protein expression data. In this blog post I will [...]
Why do I need to correct my p-values?
Hi there. Advaita is dedicated to bringing you the most advanced, easiest-to-use bioinformatics tools out there. And that includes educational materials designed to help you take advantage of all the powerful features we offer, including p-value correction factors. This [...]
Wayne State and Advaita Researchers Can Distinguish Between Aggressive and Less Aggressive Cancer
Advaita Bioinformatics is a leader in the interpretation of high-throughput biomedical data including variant interpretation, pathway analysis, and disease subtype discovery. In a breakthrough in cancer diagnosis, a technology developed by a team of researchers from Wayne State University and [...]