Genome Biology recently published a peer-reviewed paper containing a comprehensive benchmarking and comparison of 13 widely-used pathway analysis methods across more than 1,000 analyses. We highlight the most important findings below. The problem: Many high-throughput experiments compare two phenotypes [...]
How are you currently analyzing your RNASeq and proteomics data? Are you currently using one of the many free tools available for pathway analysis, such as DAVID? Or, are you perhaps using Qiagen's Ingenuity Pathway Analysis (IPA)? If yes, [...]
My previous post, Pathway Analysis vs Gene Set Analysis, ended with an interesting question: has anybody really compared side-by-side gene set analysis methods and pathway analysis methods on the same data sets? Well, the answer is: not yet! The [...]
To some, pathway analysis and gene set analysis are synonyms. However, there are important distinctions between these two groups of methods, and they provide different results. This is part of a series of articles on pathway analysis methods. Pathway [...]